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Symbol
Name
ID
Gpx1
glutathione peroxidase 1
MGI:104887
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Leukocytosis
Acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Acute myeloid leukemia
Lymphadenopathy
Abnormality of the spleen
Splenic infarction
Splenomegaly
Subacute progressive viral hepatitis
Acne
Skin rash
Osteomyelitis
Recurrent infections
Recurrent bacterial infections
Disease(s) Associated with GPX1
acute lymphoblastic leukemia
acute myeloid leukemia
hepatocellular carcinoma
multiple myeloma
pseudoxanthoma elasticum
sickle cell anemia

Mouse Phenotypes
immune system phenotype
increased inflammatory response
Availability Mouse Genotype
Gpx1tm1Kola/Gpx1tm1Kola *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory